Monday, December 30, 2019

Essay on Wedding Speech Delivered by the Brother of the...

Wedding Speech Delivered by the Brother of the Bride Good evening ladies and gentlemen, Im Neal, the brides brother. On behalf of my mother, Mrs. Lian White, I wish to thank you all for coming to celebrate this special occasion with us. We are so happy that so many of our friends and relatives are able to come here to enjoy this splendid occasion with us. Today seems like a magical dream. This morning, I proudly walked my sister down the aisle to marry Paul, the man whom she loves so much. It was so beautiful to watch them exchanging their vows in that beautiful stained glass church. Its marvelous seeing these two good people come together. The Bride and Groom Susie is a gem in our family, a blessing to both her parents and†¦show more content†¦Susie has been a good sister to me. I will miss her wit and good company, especially when South Park is on. Susie, Im sorry but the higher authorities will not allow me to do Cartmans German dance to honor this occasion. Susie and I have been so close that were almost telepathic. We used to simply exchange looks at each other to communicate jokes. But lately shes been a little distant. her eyes like those of Skywalker look far far away to . Rowville. . Paul, I am so glad that you are marrying my sister. Paul and I have been good friends for a long time. He is a hardworking, talented, and ambitious young man. He not only has a good career path in I.T. but also a place in the Guinness World Book of Records as the holder of the biggest CD collection. But, above all these things, he loves my sister first and desires that she have the best. I know that my sister has found in you a partner, a trusted friend, a husband who will love her, honor her, cherish and take good care of her. (face audience) I believe this because when he was courting my sister, he honored my family, my sister, and his God by being patient like Jacob. He waited for the right and appropriate time to ask for my sisters hand in marriage last year. If my father, Dr White, were alive today he would be proud to give his daughters hand in marriage to you. Instead, today I have that honor. The in-laws Mr and Mrs Theil (Pauls parents). I am so happy that myShow MoreRelatedEssay on Wedding Speech Delivered by the Brother of the Bride710 Words   |  3 PagesWedding Speech Delivered by the Brother of the Bride For those of you who dont know me Im Annas brother Kevin and Im here today to say a few words on behalf of our father. Unfortunately Ron is unable to be here today due to ill health. Nevertheless it goes without saying that he passes on all his love and best wishes to Anna and Melvin on their special day. When Anna asked me to give her away I was deeply honored. But all I could think was God Ill have to make a speech. 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Sunday, December 22, 2019

Human Resource Report Writing Human Resources - 3014 Words

Human Resource Report Writing Introduction Human resource management (HRM) in an organisation is concerned with the effective management of the employees in order to maximise the performance of the organisation. This department of the organisation covers various operations such as recruitment and selection, health and safety, training and development, performance appraisal, job evaluation and the human resource planning. The modern HRM is usually concerned with the workforce practices, educating and training the workforce and enabling them to fulfil all the potential that they had (Mello, 2014, p. 25). This report will focus typically on the human resource management of the organisation, and would critically evaluate and analyse the†¦show more content†¦It is important to study the barriers to develop effective practices of human resource and to implement the changes that would acquire the technical know-how with respect to the theoretical knowledge. Critical Analysis and Evaluation of the Concept of HR Strategy Having the right personnel in the organisation at the right time and place is the most important ingredient that results in the success of the organisation. The human resource management presents the workplace with the number of challenges (Bamberger, Biron Meshoulam, 2014, p. 71). One of the most important challenges faced by the organisation is to create a highly central role for the human resource that would be in terms of their strategy and would simplify the business success. The strategic human resource management (SHRM) focuses on various issues which include the practices and strategic management, involving HR functions, development and values that add to the performance. Human resource department of any organisation is criticized for effective development of policies so that the objectives of the organisation could be achieved effectively. 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Saturday, December 14, 2019

Case Study of Alliance Boots Plc Free Essays

string(60) " growth opportunities in selective new high growth markets\." ALLIANCE BOOTS PLC: INTRODUCTIION: Alliance Boots is a leading international pharmacy-led health and beauty group serving a wide range of products and services to customers over 100 years in the UK. We are trying to identify how the Boots works internally and externally to reach its goal. We are also trying to find out how the Boots motivates its employees to be productive. We will write a custom essay sample on Case Study of Alliance Boots Plc or any similar topic only for you Order Now We will also discuss its organizational structure and design to communicate each other function of the organization. We will discuss its appraisal system and organizational record keeping. We will also find out about its brand image to the stakeholder. Customers are at the heart of their business and they are devoted to providing extraordinary customers and patients care by offering innovative products ‘Only at Boots’ with exceptional values. People are their strength and tell us that Boots is a excellent place to work. They always aim to be the employers of choice by attracting and retaining the most talented and passionate people. BACK GROUND OF THE COMPANY: Boots had established its roots in the mid-19th century by John Boot, an agricultural worker, at Nottingham, in the UK. He opened a small herbalist store on Goose Gate in 1849. After John’s death in 1860, his widow, Mary, continued trading, with the help of her young son, Jesse, who became a full partner when he was 21. The store continued to thrive. In 1877, Jesse took sole control of the Boots. In 1920, he sold Boots to the United Drug Company of America. In 1933, the United Drug Company sold its holding in Boots to a group of British financiers led by John Boot, Jesse’s son. Under John’s chairmanship, the first overseas store opened in New Zealand in 1936; key brands No7 and Soltan was both launched in the 1930s. He also continued his parents’ tradition of staff welfare – improving working conditions, reducing hours and introducing pensions for all employees. More recent decades, the introduction of successful brands such as 17 cosmetics and Botanics and new business ventures such as Boots Opticians are more popular to the customers. A new chapter in Boots history started on 31st July, 2006with the merger with Alliance Unichem, to become part of Alliance Boots, an international pharmacy-led health and beauty group. Their product and services are Health and beauty, Personal care, Cosmetics and toiletries, Baby care, Dental health care, OTC and Prescription medicines, Perfumes, and Skin care. (www. bized. co. uk,) MISSION: Their mission is to be the world’s leading pharmacy-led health and beauty group. They seek to develop their core business activities of pharmacy-led and beauty retailing and pharmaceutical wholesaling and distribution across the world and become a significant player in many leading international markets. PURPOSE: Their purpose is to deliver products that help people look and feel their best. VALUES: They believe in making a difference for the well being of the communities they serve. The core values are described below. * PARTNERSHIP: It includes respect, understanding and working together. They create and build value through partnerships and alliances, inside and outside the business. * TRUST: The essence of the way they do business. People trust because they deliver on their promises. * SERVICES: They hold high standards of care and service for customers and their people. * ENTREPRENEURSHIP: They are innovators, seeking new challenges and having a winning entrepreneurship. SIMPLICITY: They are proud of being lean and efficient, uncomplicated and easy to do business fairly. (www. allianceboots. com) AT A GLANCE: * Operating over 20 countries. * It has115, 000 employees. * Operating more than 3,250 health and beauty retail stores. * Dispensing more than 245 million items each year. * 1500 Stores in the UK and Irish Republic. * Serving 420 million customers (pa). * Operat ing over 360 pharmaceutical wholesale distribution centers. * Cash generated from operation ? 1130 million. * Revenue is ? 22. 5 billion. * EBITDA is ? 1,360 million. * Trading Profit is ? 1,074 million. www. allianceboots. com) BUSINESS ENVIRONMENT OF THE BOOTS: The organizational environment consists of internal and external environment. Alliance Boots operates in highly attractive markets with potential for significant long term growth. The Company expects to increase life expectancy and product innovation to continue to drive demand for prescription medicines and related healthcare services. At the same time, they believe that a growing customer focus on personal well being will drive demand for health and beauty consumer products and related services. Fig: The Organizational Environment of Boots: Legal Environmental Technological Political Social Economic External Environment Communication External Environment ————————————————- Innovation Strategy Change Internal Environment (Writer’s observation) INTERNAL ENVIRONMENT: In order to sustain an organization, it is necessarily to adapt internal structures, process and behaviors to enable to cope with complexity and the pace of external change. It is concerned about organization’s strategy, teamwork, management, leadership style, working practices, empowerment, employment patterns, etc. * STRATEGY: Johnson et al (2008) say that strategy is the direction and scope of an organization over the long term, which achieves advantage in a changing environment with the fulfilling stakeholder expectation. The Boot’s strategy is to focus on its two business activities of pharmacy-led health and beauty retailing and pharmaceutical wholesaling and distribution, while increasingly developing and internationalizing product brands to create a third dimension. * CHANGE: According to Mullins (2007), every change becomes welcomed as an opportunity for increasing efficiency and building new organizational success. Boots increased female participation in the workforce and growth of services. It also changed the sophisticated information technology where cognitive skill demands. It has created fast flat and flexible organizational design. The company plans to further increasing the number of Boots stores through new openings and pharmacy acquisitions and have also just commenced a trial with Waitrose to sell selective product ranges in each other’s stores. * INNOVATION: According to Mullins, innovations arise from technological advancements, new processes, and improvements in all major areas of organizational activity. Boots concentrates in expanding their core business in existing markets, continuing to deliver productivity improvements and other cost savings, pursuing growth opportunities in selective new high growth markets. You read "Case Study of Alliance Boots Plc" in category "Free Case study samples" Boots is always launching products in the new markets. * COMMUNICATION: Boots always focus on customers/patients needs and services. Their communication and distribution channel is well updated which improves productivity. EXTERNAL ENVIRONMENT: The external environment is the pressures of the organization from outside that can influence and affect the performance of the organization. The significant environmental pressures are the PESTEL which locates for Political, Economic, Social, Technology, Environmental, and Legal factors. * POLITICAL: The political environment of a country predisposes by the political organizations such as philosophy of political parties, ideology of government, legislation, taxation, employment law, trade union policy and activities. Boots are also affected for political decision in the UK. The UK government is cutting the employees from most of the sectors. As a result, people will have no enough money to spend on health and beauty. ECONOMIC: It is mainly concern about total GDP of the country as well as consumers’ expenditures and disposable income. It is also included currency exchange rates, tax regime, wage rates, raw material prices etc. Boots is a multinational company. So, during recession, UK’s currency rates fell down and Boots lost lots of money to exchanged currency from other country to UK. * SOCIAL: It concerns about demographic trends, lifestyle preferences, social values, distribution of incomes, education and health, labor mobility, attitude to work, discrimination trends, skills availability, etc. Boots never discriminates any employee. Boots always tries to adopt different life style in different countries, languages, traditions, people expectations etc. * TECHNOLOGICAL: The technology adopted by the industries determines the type and quality of goods and services to be produced and the type and quality of plant and equipment to be used. The technological environment influences the business in terms of investment in technology. It refers to the innovations of IT, nanotechnology, new production methods and process, level of expenditure on RD by organization’s rivals etc. Boots uses to invest more money on research and development of its cosmetics and medicines. ENVIRONMENTAL: It links to the ‘Green issue’ of the environment, reducing toxic emissions, pollution, spills, hazard prevention, disposable of wastes or rubbishes etc. Boots dedicates to reducing the carbon intensity of their business and continued to launch specific carbon reduction initiatives. For example, Boots UK launched in August 2009 an awareness campaign aimed at reducing energy use in its retail stores. In February 2010, Boots UK received the Carbon Trust Standard in recognition of recent achievements in reducing its ‘carbon footprint’. Over 50% of the waste, they create as a Group recycles. * LEGAL: It deals with international law, legislation and taxation, human rights concerns, local regulation. It also concerns international trade agreements, employment and safety law, and product safety issues etc. Alliance Boots operates in regulated markets. It could be adversely affected by changes to existing regulation, new regulation such as licensing regimes for pharmacies, prescription processing regimes. www. boots. com) ORGANIZATIONAL STRUCTURES OF BOOTS: Director Director Director Finance Director Chief Executive Health Beauty Chief Executive Legal Chief Executive Health Beauty CEO Chief Executive Pharmaceutical Wholesale Division Chairman of the Board Director Director Director Director Chief Finance Director (www. theofficialboard. com) Organizational structure is th e formal system of task and reporting relationships that controls, coordinates and motivates employees so that they work together to achieve organizational goals. (Buchanan and Huczynski, 2004. P. 874) It is the pattern of relationships among positions in organizations and among members of the organization. Structure makes possible application of the process of management and creates a framework of orders and commands through which the activities of the organization can be planned, organized, directed and controlled. Mullins (2007, p. 564) Alliance Boots has a flat organizational chart. In the structure, we can see that there are eight directors including Board of Chairman and non executive directors. Under Board of Chairman, there are six Chief Executives who are responsible to report to Chairman. All the Executives are the same level in decision making. This structure helps Boots to do better communication between top management and employees as well as increased team spirit too. Hence, we can see less bureaucratic power which helps to make decision easily. It also improves sound coordination and timely passing information among the different department within the Boots which increases productivity. This flat structure is mostly helpful to do faster responses to changing condition. This flat structure has demerits in Boots. Here, workers may have more managers for one job which creates confusions. It is mostly helpful for a small organization but Boots is such a large organization, where it will have demerits. As a result, this will reduce the growth of the organization. (www. learnmanagement2. com) (www. blurtit. com) MOTIVATIONAL FRAMEWORK: MOTIVATIONAL Individual Colleagues The Manager Customers Organization FRAMEWORK (www. ashridge. org. uk) ORGANIZATION: The organization will provide the structure and processes such as performance management and reward schemes, training, interesting work. In the organization, leaders and managers must earn the respect of others, create an appropriate working environment and provide opportunities for people to grow and develop. THE INDIVIDUAL: Individuals need to be more open about share values with colleagues and managers. Organizations need the accurate strategy and processes that make it abundantly clear that individuals have a responsibility for their own development. THE MANAGERS: The Boss provides a crucial role in the motivation process not only acting as a role model but valuing each of colleagues in a way that makes them feel motivated. COLLEAGUES: Colleagues can play a crucial role in motivation at work. By sharing skill and ability, every employee will be motivated in the work place. THE CUSTOMERS: People will be motivated by feedback from both internal and external customers and clients. We should regularly review and share the results of feedback with staff. FACTORS AFFECTING EMPLOYEES PRODUCTIVITY: The proportion that measures the efficiency of the resources concerned in production of products and services is called productivity. It is also the ratio of inputs and outputs of the production. (www. ayushveda. om) The factors that affect the employee productivity are as follow: * TRAINING AND DEVELOPMENT: If the employees are not trained properly in their particular job role, then the organization cannot get the benefit from the employees. Sometimes Boots cannot get enough time to schedule the training timetable. COMMUNICATION: There will be constant communication among top management, middle management and the em ployees. But sometimes there is miscommunication or take time to communicate within the Boots because of managers’ holiday, Internet break down etc. * WORK LIFE BALANCE: If the husband or wife works together and there are kids, there will be a problem to match the time table. Boots gives priority to those families. * PAY AND BENEFITS: If the employees get under pay, a late payment, or wrong payment, then they will not be encouraged to perform better the job. * REWARD AND RECOGNATION: Sometimes employees are not rewarded for meritorious services which create employees opposition to complete the job. * WORKING ENVIRONMENT: If the working environment is not suitable for employees or the coordination and cooperation is lacking, the productivity will be low. EQUALITY AND DIVERSITY: If there is any discrimination, the productivity will decrease and employees will dissatisfy. Boots strictly follows the rules and regulation about equality. * OTHERS: There are few more factors which affect the productivity, such as poor management, slow decision taking, lack of trust, stress level, conflict, frustration, etc. WAYS OF MOTIVATING KEY EMPLOYEES IN BOOTS An organ ization has many attributes to its success one of which is motivation of staff of the organization. Boots has various ways of motivating their workers leaving them satisfied which encourage them to go ahead and deliver. * TRAINING AND DEVELOPMENT: Boots provides an online module and training for their staff. This enables them to fulfill their potential at work. The organization makes a significant investment in the development of a range of training. This helps new employees of the organization feel as part of the team and makes them more confident. This year, Boots put additional investment into developing their pharmacists and registered technicians supporting them with their continued professional development. DISCOUNT FOR STAFF PURCHASES: Employees get discounts for purchases on Boots and non-boots products. They obtain 12% discount on Non-boots products and 25% discount for boots products. Every employee, within a year gets double discounts for 2days, which means 25% and 50% for non-Boots and Boots products respectively. This makes them want to stay in the organization. * HEAL TH INSURANCE: Boots believes that their responsibility is to look after their colleague’s health which will help them deliver better customer service. This is particularly beneficial to the employees though this is not compulsory. It encourages them to stay with the organization hence longevity of service, intimate working knowledge and greater output. (www. boots. com) * RETAINING AND PROMOTION: The organization is decidedly particular about recruiting, retaining and promoting diverse employees in the organization. Therefore they strive for this through hard work and hence contribute enormously to the success of the organization. * ATTRACTIVE REMUNERATION: Salary is also another factor that encourages employees to work. If they are well paid they feel like coming to work coupled with a enjoyable working environment at Boots, their employees get an increase in salary every year especially when the economy is stable or growing. * HEALTH AND SAFETY: Boots always provide the right equipment to do the job. All the training regarding health and safety provide every employee to protect them as well as customers. (www. allianceboots. com) APPRAISAL SYSTEMS OF BOOTS: As mentioned above Boots appraises its employees once a year. They are informed when they are going to be appraised and what is expected of them. A form is given to each line manager for every employee just to tick the most suitable one. It describes the employees work performance. Feedback is given to employees, so they will know where to improve. The performance management cycle of Boots Plan for performance appraisal Informing employees about appraisal Feedback and working to achieve goal Performance appraisal of employees Appraisal systems depend upon the individual performance which includes quality of services, customer care knowledge, flexibility of working time, competences, skills, learning achievement, relationships with colleagues etc. ORGANISATIONAL RECORD KEEPING: It is where an organization records information from the time it creates to the time of its disposal. Record keeping is truly essential for an organization because it helps keeps the organization on track and thus achieves organizational goals. Record keeping helps the organization to monitors its financial transaction. In Boots, record keeping uses for verification financial transaction and recording information about employees such as employees personal data, training records, how many times an employee has been absent. Boots keeps its records for two years then at the end of the two the last year records destroyed and a new one is started again. (http://en. wikipedia. org/wiki/Records_management) Boots always keep employees personal data secretly and maintain the rules and regulation of the Data Act. All employees have personal record file where all the information are stored in secret. (www. 123helpme. com) CONCLUSION: Boots has a outstanding reputation about health and beauty products at the UK as well as all over the world. It is a delightful place to work everyone says. They have to work closely with manufacturers and pharmacists to improve health among the local communities as well as national level. Boots should give priorities about customers’ loyalty, retention, communication and in store marketing. In the current economic recession in the UK, they have to monitor all the financial activities to minimize the cost. There will be commitment and clear indicators from top level to lower level. Motivation is essential to business success. Boots needs to pay more attention about employees’ learning and development to meet the future demands of the organization. How to cite Case Study of Alliance Boots Plc, Free Case study samples

Thursday, December 5, 2019

Filipino People and Alfredo Salazar free essay sample

Bienvenido Santos (In which I display my mediocrity. The author, Mr. Santos, was asked to speak before an audience in Kalamazoo, MI one October when the war was still on. On the same night he met another Filipino – Celestino Fabia, a farmer. Mr. Santos was surprised to see a man who travelled really long just to hear him talk. In the course of the discussion, the man asked, in sporadically incorrect English, how the Filipino women of today were different from the stereotype he was familiar with. Mr. Santos replied that although they differ in the exterior, both women of different eras bear the heart and soul of a modest Filipina. Mr. Fabia was pleased. After the lecture, Mr. Fabia told Mr. Santos about his farm and his family and invited him over to his house, repeatedly saying that his wife, Ruth, will be pleased to meet â€Å"a first class Filipino†. We will write a custom essay sample on Filipino People and Alfredo Salazar or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page He also told him about his son, Roger, with pride. Mr. Fabia picked Mr. Santos up the next day and during the course of what seemed to be an endless journey to the distant farm, Mr. Santos became aware of Mr. Fabia’s life in the Philippines. He was a spoiled brat and the black sheep of the family. He lived in an old Visayan town where there are no apples. But there are coconut trees and roosters cooing early in the morning, and there was his family. They finally arrived in the farm, the fragrance of apples diffusing all over the place. Mr. Santos noticed how Ruth’s hospitality and kind-heartedness was almost Filipino and how adorable Roger really was. In their humble home, he also found a picture of an anonymous Filipina wearing a traditional costume – another manifestation of how dire Mr. Fabia’s nostalgia is. He bade farewell to the family and Mr. Fabia took him back to the hotel. He offered to send news to his family when he got back to the Philippines but Mr. Fabia refused, saying that they might have already forgotten him. They shook each other’s hand and said goodbye. - The scent of apples in the story  The Scent of Apples  refers to the low paying ype of jobs that Filipinos had to take when they came to America. Picking fruit was one type of job; therefore, the literal scent of apples indicates the profession of the worker who spends all his time in the orchard picking apples Alfredo Salazar son of Don Julian, a more than 30 years old man and a bachelor. He is engaged to Esperanza but him still fleeting to Julia Salas Esperanza wife of Alfredo Salazar. She is a homely woman, literal minded and int ensely acquisitive. She is one of those fortunate women who have the gift of uniformly beauty Julia Salas sister-in-law of Judge Del Valle. She is the other girl of Alfredo Salazar that remains single in her entire life Don Julian an old man, a father of Alfredo Salazar and Carmen. lt;/pgt;lt;pgt;\ Carmen sister of Alfredo Salas Judge Del Valle brother-in-law of Julia Salas Donna Adella sister of Julia Salas. She is small and plump, a pretty woman with a complexion of a baby with a expression of a likeable cow Calixta note-carrier of Alfredo Salazar and Esperanza Dionisio husband of Donna Adella. Vicente husband of Carmen Brigida Samuy She is the illusive woman whose Alfredo is looking for. Paz Marquez-Benitez, in her masterpiece Dead Stars, did not only write about a love story. Most importantly, her writing reflects the time in which the literary work was written along with the language, the norms and the way people think. It serves as a literary time machine for readers as it enables them to understand how courtship, marriage and fidelity were viewed through the early 1900 standards. It renders a sound comparison between the past and the present, the existing modern culture and the fading, almost obsolete tradition. Although the comparison and contrast provides a good critical foundation, another highly significant aspect of this short story involves the main character, Alfredo Salazar, which, always applies to whatever era, hence the focus of this paper. His confusion, weakness and unreasonableness are innate flaws of humans. Perhaps one of the many reasons why this work is timeless is that readers never fail to see a part of them in Alfredo Salazar’s character, making the

Thursday, November 28, 2019

Date Rape Essays (2797 words) - Rape, Date Rape, Acquaintance Rape

Date Rape OUTLINE This research paper is about the issue of acquaintance rape, also known as date rape. In this papers context, I will define acquaintance / date rape. I will discuss how and why it occurs. This paper explores the laws and the judicial system and how they work. I will discuss ethics, myths about acquaintance / date rape, and victims reactions. I will discuss how misinterpretation of sexes are comprehended and misunderstood. I will show how the movie industry and the news media glorifies rape cases. Finally, I will look into false accusations of rape by women against men. DATE RAPE Date rape can generally be defined as occurring whenever a man forces his date to have sex with him against her will. Some people expand this definition to include forced sex by any acquaintance, whether it be in context of a date or not. Despite the simple definitions, however, there is a great deal of controversy over the exact legal and moral implications of date rape or acquaintance rape. The legal definition of date rape is extremely limited and it tends to place the burden of proof on the victim. A date rape victim will have a difficult time in court if the defence attorney can show a lack of evidence or can imply that the women is loose or immoral in any way. This, in prosecuting a date rape, it helps if the victim has visible bruises or is a woman of shining charter, because otherwise the strict definitions of rape will prevail in court.1 Whereas the legal view threats date rape as if it was a regular rape by a stranger, moral definitions tend to take other factors into account. For example, date rape raises a number of ethical questions regarding the line that divides normal courtship behavior from violent assault. Many offenders argue that they forced their dates to have sex with them because they believe that is how women like being treated. despite this, however, it is obvious that there is a difference between mutual consent between partners and own person using force against the other. As noted by Susan Jacoby, even the most callow youth can understand the difference between a halfhearted no, we shouldn't and tears or screams.2 There are a number of moral questions which are raised by the issue of date rape. For example, it is obvious that a rape has occurred if the man has used physical force. However, it is also rape if he has used coercion or threats or has gotten his date drunk in order to have sex with her. Because of the moral difficulties in defining date rape, lots of women are even confused about whether they've been raped. Moral definitions of date rape are often attached to ideological schools of thought. For example, there is a feminist perspective on date rape that holds it, as well as rape in general, is the product of a mans traditional dominance over women.3 This point of view has sparked controversy, however, for example, Murry Rothbard criticizes the feminist definition of date rape because it suggests that all men are potentially guilty of committing the crime. Rothbard claims that this extremist opinion often results in men being unjustly accused of rape. For example, it is argued that there are cases in which a women doesn't say no and doesn't resist, but latter claims that she was raped anyhow, simply because she had been influenced by feminist thinking in the mean time.4 John Leo also disagrees with the feminist definitions of date rape. According to Leo, the feminists failure is in there emphases on rape as an act of political or social oppression.5 From this view point, the feminist argue that sex has nothing to do with the act of rape. Leo counters the argument by claiming that sexual drives are obviously involved in the act of rape. In addition, Leo promotes a biological definitions of date rape, which claims that rape exists because men have a high sex drive and are intimately aggressive. Nancy Rue provides a definitions for date rape which seems to straddle the middle ground between these extreme points of view. According to Rue, date rape occurs whenever a man demands sex

Monday, November 25, 2019

Discuss The Role Of Parents And Peers In Childhood And Adolescent Development And Compare The Influence Of Each The WritePass Journal

Discuss The Role Of Parents And Peers In Childhood And Adolescent Development And Compare The Influence Of Each Introduction Discuss The Role Of Parents And Peers In Childhood And Adolescent Development And Compare The Influence Of Each IntroductionParental InfluencePeers InfluenceConclusionReferencesRelated Introduction   The degree to which our parents and our peers influence our development has long been debated in scientific literature. Brofenbrenner’s (1974, 1976) ecological systems perspective holds that in order to truly understand human development, the entire ecological system in which it grows must be taken into account. For a child, this ecological system includes both the influence of their parents and their peers, which are considered to be microsystems within the child’s environment. Both parents and peers may influence a child through exhibiting or reinforcing certain behaviours or attitudes or by disapproving or forbidding particular behaviours or attitudes. Parents and peers can also influence child development in unique ways. For example, through different parenting styles or through peer pressure. This essay will discuss and compare parental and peer influence on child and adolescent development. Parental Influence   One of the most influential studies that demonstrated the impact that adult behavior can have on the development of children was carried out by Bandura, Ross and Ross (1961) at Stanford University. It was found that children who observed a adult role model acting physically and verbally violent to a ‘Bobo’ doll were significantly more likely to also act violent toward the doll. Furthermore, it was found that boys were more likely to act violently after observing male adult models than female adult models and would engage in more violent acts that girls. This study demonstrated the strong social influence of adult models on young children and the gender differences that accompany this influence. This influence has come to be known as social learning theory (Bandura, Ross and Ross, 1961) and has been very influential in understanding how children may learn certain behaviours. The theory postulates that children develop certain behaviours and attitudes through observati on and by modelling these behaviours and attitudes on those they look up, such as parents (Bandura, 1977). Social learning theory has been repeatedly shown mediate parental influence on child development. For example, Scaglioni, Salvioni and Galimberti (2008) found that parental attitudes about food had a significant impact on their children’s attitudes toward food. Furthermore, parental attitudes also had an impact on a child’s body satisfaction levels. In both cases, social learning theory can explain the strong parental influence on child behaviours such as a aggression, eating habits and self-esteem. However, the theory does not always stand true. For example, it cannot be used to explain why positive parent behaviour and role models can sometimes result in negative child behaviours. In addition to the social learning theory, it has also been theorised that parenting styles may influence a child’s development. Parenting styles have been classified into four different categories (Maccoby and Martin, 1983; Baumrind, 1991): authoritative, authoritarian, permissive and neglectful. Authoritative parents are demanding, but not restrictive and are highly involved with their child. In contrast, authoritarian parents are both demanding and restrictive, being far more untrusting of their children. Permissive parents tend to be responsive but not demanding of their child. Although they are warm and child-centred in their approach, they also have a lack of parental control. Finally, neglectful parents are neither demanding nor responsive, typically demonstrating complete un-involvement. Parenting styles have been found to have an effect on adolescents’ achievement strategies (Aunola, Stattin and Nurmi, 2000), with adolescents with authoritative parents demonstr ating the most positive strategies and adolescents with neglectful parents demonstrating the most maladaptive strategies. The negative impact of a neglectful parenting style has been replicated in later studies. For example, Hoeve et al. (2011) found that a neglectful parenting style was linked to a higher level of delinquency in males. It was also reported that a significant long term relationship existed between a father’s neglectful parenting approach and delinquency in male children. This gender-specific influential relationship can be compared to the strong gender-specific role model effect predicted by social learning theory. However, the parenting styles theory is very reductionist and does not take into account other influences on childhood development and achievement, such as the socioeconomic status of the parents (Davis-Kean, 2005). Peers Influence Peer relationships also have the power to influence a child’s development for better or worse. For example, bullying and victimisation during the school and adolescent years has been shown to have a negative impact upon several aspects of a child’s development. In a large scale questionnaire study, Rigby (2000) found that frequent bullying by one’s peers had a significantly negative effect on young people’s mental health. It was also found that this negative effect was exacerbated by perceived low social support, demonstrating that elements outside of the bullying environment interact with this peer influence. This study used a large and representative sample meaning that the results are likely to be highly generalisable. Bowes et al. (2010) found that a warm and positive family environment was able to reduce the negative effects of bullying by peers, suggesting that positive parental influences may have the power to overcome negative peer influences. In c ontrast, there is little evidence to suggest that negative peer influences have the power to overcome positive parental influences such as high levels of support and guidance through the tumultuous adolescent period. An additional peer influence that has been shown to have an effect on child development is known as sociometric status. Sociometric status can be defined as how liked or disliked a child is by his or her classmates and peers (Asher and Dodge, 1986) and has been linked to numerous aspects of development. For example, Wentzel (2003) carried out a longitudinal study of the effect of sociometric status on academic achievement and adjustment at school. It was found that sociometric status has a significant effect on such measures as irresponsibility and classroom grades. Nelson and Dishion (2004) found that socio-metric status was able to predict how well 9-10 year old male children adapted in later life, suggesting that peer influences can last well into adulthood. Longitudinal studies have strength in the richness of data they are able to provide during an extended time period. However, the un-controlled environment means that the results can be vulnerable to confounding variables. What is more, despite providing some useful data sociometric status is unlikely to give an accurate picture of peer influence. The status is based on the opinion of other children within a school environment and does not account for the opinions of peers a child may relate to outside of school, for example at extra-curricular clubs or friends who do not attend the same school as they do. The effects of peer pressure on child development have also been investigated. For example, Gardner and Steinberg (2005) found that exposure to ones’ peers doubled the amount of risk taking behaviour exhibited by adolescents. However, these results were later refuted by Bot et al. (2007) who found that peer pressure had no significant effect on whether a young person would engage in underage drinking. In contrast, it was found that modelling peers’ drinking behavior did have a significant impact. Therefore, peer pressure may exert its influence on child development through modelling rather than by active encouragement by peers to take part in negative or risky behaviors. This suggests that peer pressure may be a more passive than active influence, as adolescents seek out other peers on which to model their own behavior, some of which may be negative or dangerous. Conclusion The literature pertaining to the influence of parental and peer influence on child development does reveal some replicable trends, which strongly suggest that a poor and neglectful parenting style has a negative effect on many different aspects of child development. Furthermore, when a child experiences isolation from their peer group either as a result of bullying or low sociometric status, they are also likely to suffer from negative outcomes. Therefore, the evidence appears to suggest that neglect and isolation from either peers or parents has a negative effect on child development, whereas a supportive environment will have a positive effect. Peer and parental influence also have a strong gender-bias in common, meaning that male peers and parents tend to have a stronger influence on the male child, whereas female peers and parents have a stronger influence over the female child. The most likely scenario is that both parent and peers have a strong influence on a child’s dev elopment, although these influences peak and trough during certain age periods. For example, peer relationships become increasingly more influential and important as children begin to enter adolescence (Brown, 2004) and as a result, elements such as sociometric status and bullying may exert more of an influence than parental behaviors or attitudes. However, the evidence suggesting that positive parental influences may reduce negative peer influences suggest that if parents are able to buffer children by providing a warm, encouraging and safe home environment, future negative peer influences may be less likely to have an impact on their development. References Asher, S.R. Dodge, K.A. (1986). Identifying children who are rejected by their peers. Develop mental Psychology, 22, 444-449. Aunola, K., Stattin, H. and Nurmi, J-E. (2000). Parenting styles and adolescents’ achievement strategies. Journal of Adolescence, 23, 205-222. Bandura, A., Ross, D. Ross, S.A. (1961). Transmission of aggression through imitation of aggressive models. The Journal of Abnormal and Social Psychology, 63(3), 575. Bandura, A. (1977). Social Learning Theory. Englewood Cliffs, NJ: Prentice Hall. Baumrind, D. (1991). The influence of parenting style on adolescent competence and substance use. Journal of Early Adolescence, 11, 56-95. Bot, S.M., Engels, R.C.M.E., Knibbe, R.A. Meesus, W.H.J. (2000). Sociometric status and social drinking: Observations of modelling and persuasion in young adult peer groups. Journal of Abnormal Child Psychology, 35(6), 929-941. Brofenbrenner, U. (1974). Developmental research, public policy, and the ecology of childhood. Child Development, 45(1), 1-5. Brofenbrenner, U. (1976). The experimental ecology of education. Teacher’s College Record, 78(2), 157-204. Brown, B. (2004). Adolescents’ relationship with peers. In: R. Lerner L. Steinberg (Eds), Handbook of Adolescent Psychology, (pp. 363-394). New York: Wiley. Davis-Kean, P.E. (2005). The influence of parent education and family income on child achievement: The indirect role of parental expectations and the home environment. Journal of Family Psychology, 19(2), 294-304. Gardner, M. Steinberg, L. (2005). Peer influence on risk taking, risk preference, and risky decision making in adolescent and adulthood: an experimental study. Developmental Psychology, 41(4), 625-635. Hoeve, M., Dubas, J.S., Gerris, J.R.M., van der Laan, P.H. Smeenk, W. (2011). Maternal and paternal parenting styles: Unique and combined links to adolescent and early adult delinquency. Journal of Adolescence, 34(5), 813-827. Maccoby, E.E. Martin, J.A. (1983). Socialisation in the context of the family: Parent-child interaction. In P.H. Mussen (Ed.), Handbook of Child Psychology (pp. 1-101). New York: Wiley. Nelson, S.E. Dishion, T.J. (2004). From boys to men: Predicting adult adaptation from middle childhood sociometric status. Development and Psychopathology, 16, 441-459. Rigby, K. (2000) Effects of peer victimisation in schools and perceived social support on adolescent well-being. Journal of Adolescence, 23(1), 57-68. Wentzel, K.R. (2003) Sociometric status and adjustment in middle school: A longitudinal study. Journal of Early Adolescence, 23, 5.

Thursday, November 21, 2019

Research and analyse Google company Essay Example | Topics and Well Written Essays - 750 words

Research and analyse Google company - Essay Example Beyond the founders, Google has diverse stakeholders. The stakeholders influence the decisions of the organization significantly. Stakeholders of the organization experience a set of positive and negative ramifications in their positions (Morrow, 2013). Therefore, the stakeholders have both benefits and challenges posed by the organization. Stakeholders of this organization entail users, investors, and employees (Morrow, 2013). These are the key stakeholders of the Google organization. Users are key stakeholders in Google. Google has a huge amount of users due to its diversity of services. The company provides diverse programs, tools, and information for the benefit of users (Morrow, 2013). In this case, the diversity expands the number of users in the company. This organization records a huge number of users that exceeds a total of a billion. Google has a set of positive effects towards the users. Each user benefits significantly from the information disseminated by Google (Morrow, 2013). The advertisements, research, and scholarly details facilitate the knowledge and awareness of each user. Programs and tools in Google enhance the technological expertise of the users (Morrow, 2013). The programs and tools also enhance convenience of communication amongst the users (Morrow, 2013). Evidently, Google users have maximum benefit from the company’s provisions. ... Investors are also key stakeholders of Google (Morrow, 2013). The company has outstanding benefits towards the investors. In the past year, the company raised an total of 14.4billion in its revenue (Morrow, 2013). This is a 36% growth of the company, after the culmination of the previous year. Definitely, investors benefit from the massive financial rewards from the company. However, investors cannot predict the progress of the organization due to the rampant social change that initiates shifts in users’ preferences (Morrow, 2013). Competition is already emerging from companies that offer the same services as Google. Nevertheless, Google is kept secure as it records an aggregate of 86% of satisfied customers in the modern society (Morrow, 2013). Employees are key stakeholders in Google (Morrow, 2013). They influence decision making in the organization (Morrow, 2013). Employees in Google benefit from the company’s capability to reward and motivate them. Google offers inc entives that motivate the loyalty of the workforce (Morrow, 2013). Each employee in Google is motivated to serve the organization. Despite this fact, employees in Google have been resigning rampantly (Morrow, 2013). The past year resignations are attributed to extreme bureaucracy within the organization. Therefore, Google employees are negatively affected by bureaucracy (Morrow, 2013). Evidently, every stakeholder in Google experiences a set of benefits and challenges simultaneously. Google is a major organization in the globe. â€Å"Its operations in the USA entail massive usage of electricity† (Whelan, 2008). Therefore, Google consumes an immense proportion of that aggregate electricity in the USA. This organization has been in operation for

Wednesday, November 20, 2019

Plants and Animals Essay Example | Topics and Well Written Essays - 1250 words

Plants and Animals - Essay Example Paleoethnobotany refers to as the study of relationships between plants and animals, though the use of the archaeological records. The present human beings are aware of how people benefitted from plants for clothing, food, medicine, boats, houses, and a variety of tools and structures. Therefore, in the contemporary society, individuals try to understand the ecological and cultural dynamics of the previous food ways; techniques for producing, procuring, and managing plant resources; and the meaning that plants had to the past human beings (Merlin, 2003). Archeology and paleoethnobotany have a close relationship between themselves. Paleoethnobotany is the sub-field of archeology that deals with the study of plant remains from excavations. Therefore, archeology supports paleoethnobotany by providing the study materials, especially the plant remains. People can be able to understand the relationship between animals and plants through archeology. ... It is apparent that paleobotany differs from paleoethnobotany because paleobotany does not include the relationship between plants and animals, but only considers plant remains in their geological settings (Merlin, 2003). Artifactual and Paleoethnobotanical data A researcher depends on the collected data in order to support or test the hypothesis of a given research. For instance, there has been a need of data to support the hypothetical use of psychoactive drugs in the historical period. Researchers extract most of the data from the literature of disciplines such as archeology, anthropology, palynology, and ethnobotany. Dating of various evidences varies in relative reliability and technique. Artifactual and paleoethnobotanical data are forms of data that provide the archeological evidence for the relationship between plants and man in the previous days (Merlin, 2003). An example of the relationship is how ancient people used the psychoactive drugs. The artifactual data is the subje ct to some type of reconstruction and interpretation (Merlin, 2003). There will be a disagreement regarding the interpretation of the artistic, medicinal, religious, or other practical inspiration of an artifact. Paleoethnobotanical evidence results from the assignment of specimens to specific taxonomic groups, and verification of its putative use by human beings is sometimes contentious (Merlin, 2003). The most reliable archeological information results from the combination of artifactual and paleoethnobotanical evidences (Merlin, 2003). Merlin’s Hypothesis The evidence on use of cannabis for recreation, fiber, medicine, and ceremony is enough to go against Merlin’s hypothesis, which

Monday, November 18, 2019

Macro and micro economics Essay Example | Topics and Well Written Essays - 1500 words

Macro and micro economics - Essay Example Though, this is just a rough estimation. The utility comparison has never been accurately summarized, each writer puts down their own views. All the views are somehow correct because they are an improved notion of the first theory. So it is correct to say, Ann’s utility function is lower than peter’s. 2. Central banks have started raising interest rates as many economies picked up in 2010, to combat inflation. Explain the (opposite) effects of higher interest rates and lower inflation on the budget set and welfare of house owners with a mortgage, and assess the overall effect on them. Interest rate is the amount which is charged to the borrower by the lender and it is usually expressed as a percentage. The rate changes due to inflation. On the other hand, inflation is the general rise in the prices level of services and goods over duration of time. By increasing the interest rates, the central banks make it harder for the commercial banks to borrow money. By so doing th e money in circulating reduces hence reducing the inflation. The inverse of this is the central bank reducing its lending rates and making it possible for more banks to borrow money. This will translate to people borrow more money thus increased purchasing power. To people with mortgages it will be easier for them pay to the bank. The overall effect is that the living standards of people will improve since there enough money and its value will be okay. 3- Economics Comprehension 1 Insurance is big business in the UK. So is internet gambling? How might we explain this paradox? (Can it be explained without giving up the assumption that people’s preferences obey the von Neumann-Morgenstern axioms?) Insurance is a contract where premium is paid to the insurer to cover the occurrence a specific risk. Internet gambling includes any kind of activities that are transacted through the internet which involve placing of bets or a wager. The Von- Neumann-Morgenstern’s theory of ut ility has many assumption is one of them being continuity. This is shown by a decision maker who prefers an outcome A to other outcomes B, C. in the interval of unit a number p makes the decision maker indifferent between getting outcome B and yielding A which has a probability P, probability 1-p for C in a lottery. In the UK, insurance being a big business attracts a lot of people. 4. In modern societies, not just simple goods but also uncertain prospects (such as insurance policies) are traded, sold and bought. Show how this phenomenon can be explained by differences in risk attitude between economic agents and show how Pareto-improvements can thereby be achieved. In the modern world, different methods have been established due to high rise of risks. Insurance also involves risks making its agents involve a fee charging the users of the service involving on the risks insured. An agreement between the inured and the insurer known as the policy holder determines the claims which the insurer is legally required to pay. Risk management is important in insurance since insurance companies take over risks from customers. Risk attitude affects projects. This is because of differences in people’s attitude to risk cause conflict, and delay. This can lead to poor management of risks. Loss in insurance is depending on two variables: the number of losses that will occur in a specified period and the amount of losses given that a loss has occurred. The risk attitude depends on its

Friday, November 15, 2019

Migration Rate of Colo16 Cells Exposed to UV Light

Migration Rate of Colo16 Cells Exposed to UV Light Introduction: Cells exposed to ultraviolet (UV) rays of light often supress signalling pathways associated with inflammation as well as the immune system and as a result of activating the p38 mitogen activated protein kinase (MAPK) pathway. Radiation from UV light is from the electromagnetic spectrum and can be divided into two primary wavelengths; UVA 320 – 400 nm and UVB 290 – 320 nm. UVA rays are more dominant than UVB, however both UVA rays reaching the subcutaneous layer of skin and UVB rays reaching the dermis are known to cause the development of skin cancers via damaging the DNA of skin cells (1, 2, 3). The effect of UV light on cells can be measured by determining the time the cells take to migrate back to their normal positions after the creation of an artificial wound. An inexpensive and easy assay to perform to make such measurements is the scratch assay. The scratch assay uses a pipette tip to create an artificial gap between the cells under aseptic conditions and uses high resolution imaging devices connected to an inverted microscope to take pictures of the cells migrating at specific time intervals. The images can then be used to calculate the distances travelled under the different UV exposures and therefore a comment on how the cells were affected under the different conditions can be made (1, 2, 3, 4). In this experiment, Human squamous cell carcinoma (SSC) cells that are known to have a dysfunctional p53 proteins were taken from the epithelial Colo16 cell line and used to measure the migration distances of the cells under different UV exposures. Then the matrix metalloproteinase (MMP) inhibitor GM6001 was added to the Colo16 cells in order to determine if it had an effect on the cell migration distances under the same UV exposures (1, 3, 5, 6). GM6001 is a MMP inhibitor that inhibits the enzyme collagenase which destroys the peptide bonds of the protein collagen found in the extracellular matrix. Collagen is an important component of the connective tissue and helps the cells adhere to their surrounding surfaces. GM6001 has been shown to block the phosphorylation of the epidermal growth factor receptors (EGFR) and inhibit cell migration responses (3, 5). Aims: To determine the migration rate of Colo16 cells exposed to UV light at intervals of 12 hours over 48 hours after the creation of an artificial wound (gap). To determine the effect of the MMP inhibitor GM6001 on the migration rate of Colo16 cells exposed to UV light at intervals of 24 hours over 72 hours after the creation of an artificial wound (gap). Hypothesis: If cells from the Colo16 cell line are treated with the MMP inhibitor GM6001 then it is expected that the mean gap distance will increase when compared with untreated Colo16 cells under the same exposure to UV light due to the inhibition of collagenases that breakdown collagen and the blocking of EGFR phosphorylation. Materials and methods: As per the BIOL2299 2014 Prac 4 lab notes. Results: Raw class data for the untreated and treated Colo16 cell gap distance (mm) is shown in Table 1 and Table 2 respectively. From the class data our group was Group A shown in Table 3 and Table 4, and the mean class data along with its standard deviation values is shown in Table 5 to Table 8. Table 1. Class Untreated Colo16 Cell Gap Distance (mm). Table 2. Class Colo16 GM6001 Treated Cell Gap Distance (mm). Table 3. Group A Colo16 Untreated Cell Gap Distance (mm). Table 4. Group A GM6001 Treated Colo16 Cell Gap Distance (mm). Table 5. Mean Class Colo16 Untreated Cell Gap Distance (mm). Table 6. Class Standard Deviation (SD) of Colo16 Untreated Cell Gap Distance (mm). Table 7. Mean Class GM6001 Treated Colo16 Cell Gap Distance (mm). Table 8. Class Standard Deviation (SD) of GM6001 Treated Colo16 Cell Gap Distance (mm). Figure 1. Line graph showing the mean gap distance of Untreated Colo16 cells under different UV exposures along with the standard deviation values after the creation of a synthetic gap using a pipette tip at intervals of 12 hours over 48 hours post-irradiation. Figure 2. Line graph showing the mean gap distance of Colo16 cells treated with the MMP inhibitor GM6001 under different UV exposures along with the standard deviation values after the creation of a synthetic gap using a pipette tip at intervals of 24 hours over 72 hours post-irradiation. Discussion: From the line graph in Fig. 1, the Colo16 cells under UV radiation showed a slower decline in gap distance compared with the control. And the Colo16 cells exposed to UVA + UVB rays had the slowest decrease in gap distance over 48 hours after the creation of the artificial wound with a gap distance of only 0.200 mm suggesting that both UVA and UVB work with synergy together and the p38 MAPK pathway and therefore cause a delay in wound healing. From the line graph in Fig. 2, the Colo16 cells treated with the MMP inhibitor GM6001 exposed to different UV conditions had a delayed cell migration response when compared to the control GM6001 Colo16 cells that were not exposed to UV irradiation. This may be due to the inhibition of collagenases that help breakdown the collagen found in the extracellular matrix (ECM) of the Colo16 cells via the action of GM6001. GM6001 is a MMP inhibitor that inhibits the enzyme collagenase that normally is involved in the breakdown of collagen of the ECM. This inhibition may affect the cell migration of Colo16 cells during wound healing as a result of the collagen not being broken down by the collagenases in the ECM and therefore resulting in the cells being adhered to their surrounding for a longer time; increasing the time required to close the gap and complete the wound healing process. Discussion questions: What other ways are there to determine whether cells are migrating into the wound or proliferating into it? (Are there morphological characteristics of cell migration or proliferation?) Other ways of determining cell migration or proliferation include: 1 – Immunofluorescence staining: cells can be stained using fluorescence markers that use antibodies to bind to specific antigens associated with cell migration or proliferation such as the proliferating cell nuclear antigen (PCNA) (7). 2 – Laser scanning confocal microscopy: cells can be viewed under high resolution and the morphological features of migrating cells can be observed such as the formation of fibrin matrices, an increase of length, width and total spread of fibroblasts (7). 3 – Boyden chamber: which measures cell migration via the determination of a chemical gradient based on chemicals release via chemotaxis during cell migration (7). What is a Boyden chamber and why would you use it? Give 3 examples of where it can be used. A Boyden chamber is an in vitro chemotaxis assay that measures cell migration via the analysis of leukocyte chemotaxis, where cells are placed in pores at the top of a chamber and allowed to migrate through its pores containing chemotactic agents. After incubation the cells are stained and the number of cells that have migrated to the lower portion of the chamber (8). The Boyden chamber can be used to measure: 1 – Cell migration based on chemicals released to the cell’s surrounding, and determine if a specific chemical causes the cells to migrate towards or away from the stimulant (Chemotaxis) (8). 2 – Cell migration based on the gradient of specific extracellular matrix proteins, and determine if a particular protein causes the cells to migrate towards or away from the protein. This can be done via the coating of the chamber with the protein of choice (Haptotaxis) (8). 3 – Cell migration rate of tumour cells through the vascular endothelium toward specific chemokines (8). Describe 3 limitations of the scratch method. Some limitations of the scratch method include: 1 – Creation of an artificial wound of the same approximate width can be extremely difficult and any variance in the gap distance between the different cells at time 0 hr can greatly affect the significance of the results (4). 2 – The incubation of the cells after the creation of the wound (scratch) has to be long enough to help the cells migrate during the fastest time frame and any variance in this may lead to the cells not migrating equally, therefore affecting the results. Also, the temperature and environmental conditions of the incubator have to be at their ideal values for healthy cellular migration (4). 3 – Highly time consuming, in order for the readings to be statistically significant at least 100 readings of distance for each sample and each experiment must be repeated at least three times. As a result, this creates copious amounts of data that consumes a lot of time and energy to analyse (4). If you are investigating cell growth factors on cell migration, should serum be present in the media? Explain your answer. Yes, Serum containing the growth factors should be found in the media in order to study its effects and the growth factors should be soluble in the serum and added to the media before the addition of cells in order to be equally distributed in the solution (4). What are the main differences in investigating a scratch assay using non-transformed vs transformed cells? Transformed cells are transfected with a plasmid coding the gene of interest along with a plasmid marker before the conduction of a scratch assay, whereas non-transformed cells are investigated without being transfected with a specific plasmid (4). Apart from taking photos of the cells over time, propose another way you may be able to show cell migration. Cell migration can be shown via the conduction of an electric cell-substrate impedance sensing (ECIS) in vitro cell migration assay that measures cell migration via the creation of a wound by passing an electrical current through the cell and causing electroporation. Then cell migration is measured via the calculation of the cell’s impedance in ohms over a specific time as seen in Fig. 3 (9). Figure 3. Typical ECIS data involving the electric cell-substrate impedance sensing (ECIS) in vitro cell migration assay (http://www.biophysics.com/woundhealingpubs.php#ECIStheory). Which of the methods is the one that most labs would not use, explain why you think this would be so. Most labs would not use the ECIS in vitro migration assay due to its expensive cost and it’s relatively time consuming cell type dependant incubation times. Another in vitro migration assay that would not be used in labs is the microfluidics-based system due to its need for nanofabrication facilities and its reasonably very expensive cost (4). Conclusion: In conclusion, Colo16 cells under UV radiation showed a slower decline in gap distance compared with the control. And the Colo16 cells exposed to UVA + UVB rays had the slowest decrease in gap distance over 48 hours after the creation of the artificial wound with a gap distance of only 0.200 mm suggesting that both UVA and UVB work with synergy together and the p38 MAPK pathway and therefore cause a delay in wound healing. Whereas, the Colo16 cells treated with the MMP inhibitor GM6001 exposed to different UV conditions had a delayed cell migration response when compared to the control GM6001 Colo16 cells that were not exposed to UV irradiation. This may be due to the inhibition of collagenases that help breakdown the collagen found in the extracellular matrix (ECM) of the Colo16 cells via the action of GM6001. This inhibition caused by GM6001 may affect the cell migration of Colo16 cells during wound healing as a result of the collagen not being broken down by the collagenases in the ECM and therefore resulting in the cells being adhered to their surrounding for a longer time; increasing the time required to close the gap and complete the wound healing process. References: BIOL2299 Biology of Tissue Growth and Repair Manual, 2014. Reichrath J, Rass K. Ultraviolet damage, DNA repair and vitamin D in nonmelanoma skin cancer and in malignant melanoma: an update. Advances in experimental medicine and biology. 2014;810:208-33. Muthusamy V, Piva TJ. A comparative study of UV-induced cell signalling pathways in human keratinocyte-derived cell lines. Archives of dermatological research. 2013;305(9):817-33. Liang CC, Park AY, Guan JL. In vitro scratch assay: a convenient and inexpensive method for analysis of cell migration in vitro. Nature protocols. 2007;2(2):329-33. Grobelny D, Poncz L, Galardy RE. Inhibition of human skin fibroblast collagenase, thermolysin, and Pseudomonas aeruginosa elastase by peptide hydroxamic acids. Biochemistry. 1992;31(31):7152-4. Moore GE, Merrick SB, Woods LK, Arabasz NM. A Human Squamous Cell Carcinoma Cell Line. Cancer Research. 1975;35(10):2684-8. Chen HC. Boyden chamber assay. Methods in molecular biology (Clifton, NJ). 2005;294:15-22. http://www.cellbiolabs.com/boyden-chamber-assays http://www.biophysics.com/woundhealingpubs.php#ECIStheory

Wednesday, November 13, 2019

To Kill A Mockingbird by Harper Lee - Answers :: To Kill a Mockingbird Essays

To Kill A Mockingbird by Harper Lee Question : On giving Jem and Scout air rifles, Atticus tells them that to kill a mockingbird is a sin. Miss Maudie explains that mockingbirds only do one thing, and that is to sing their hearts out for us. Who are the mockingbirds in the story, and how have they been ‘killed’ by the society around them? Ideas : The two main mockingbirds are Boo Radley and Tom Robinson, but there are others within the storyline. Boo Radley has been shut away from the world by his father and then later his brother through an incident which occurred fifteen years earlier when he stabbed his father with a pair of scissors. The suggestion is that he had gone mad and should have been committed to an asylum. His influence in our story is all-good in that he gives gifts to the children, repairs Jem’s pants when they are caught on the fence and, of course, saves the children’s lives when Bob Ewell attacks them. Sheriff Tate recognizes the vulnerability of Boo and that any publicity would destroy him, so he says that the death was an accident. Tom Robinson is actually killed and his death is a sin committed by the whole white community of Maycomb. All he tried to do was to abide by the rules of the society in which he lived and when a black person is asked to do a chore he obeys. The main enemies of birds are cats and Lee describes Mayella as being like ‘a steady-eyed cat with a twitchy tale’ and the bird she is focusing on is of course, Tom Robinson. Lee’s description is that of a cat stalking its prey. Jem to some degree was also a mockingbird. He went with Scout to the black church in order to please Calpurnia, and the Rev. Sykes. Jem suffers in that his youthful idealism is shattered by the verdict given by the all-white jury at the trial. The pet-dog of Maycomb is called Tim Johnson, a bird-dog, who one day acts strangely because he has caught rabies. He gave pleasure to the townsfolk, but suddenly he now causes fear. So much so that even the mockingbirds are silent. Atticus shoots the dog for the good of the whole town. Question : Discrimination rears its ugly head in many forms within this story. Give examples of this. Ideas : The obvious discrimination is that of the dominant white community over the subservient black community. They are not given the same opportunities regarding education, illustrated by the visit to the Negro church where only a few can read.

Monday, November 11, 2019

Generally Accepted Accounting Principles Essay

A. What is the difference between a contribution income statement and a traditional income statement? Contribution income statement is an income statement that classifies cost by behavior (fixed cost and variable cost). Traditional income statement is sometimes called the functional income statement. It is an income statement prepared in the multiple-step or single –step income statement format which conforms to Generally Accepted Accounting Principles (GAAP) and can be used for external financial reporting. The main difference between the two is that the contribution income statement list variable costs first, followed by fixed costs. Keeping in mind that GAAP and does not permit businesses to use the contribution income statement for financial accounting – it is used only for internal decision making purposes. B. What is the difference between absorption costing and variable costing? Absorption costing is a costing method where product cost includes all the costs to acquire products and get them ready to sell regardless of whether the costs are variable or fixed. Generally Accepted Accounting Principles requires business to use absorption costing for financial accounting. Variable costing is a method of costing where only the costs to acquire products or to get them ready to sell that vary with output are treated as product costs. In other words, only variable product costs are treated as product costs. For manufactures, the difference between absorption costing and variable costing is significant. For example, when Caterpillar uses absorption costing to determine the cost of manufacturing, its product cost includes the direct material, direct labor, variable manufacturing overhead, and fixed manufacturing overhead cost incurred to make the bulldozer. These costs are added to inventory and they are not expensed as cost of goods sold until the bulldozer is sol. However, when Caterpillar uses variable costing, product cost, includes only direct material, direct labor, and variable manufacturing overhead costs. Under variable costing all of Caterpillar’s fixed manufacturing overhead cost is treated as period cost. When Caterpillar uses variable costs are added to inventory (direct material, direct labor, and variable manufacturing overhead). Under variable costing, Caterpillar expenses fixed manufacturing overhead as it is incurred just like it does other period cost such as selling and administrative expense. F. What is the contribution margin ratio and how does it differ from the contribution margin? Contribution margin is the amount remaining after all variable costs have been deducted from sales revenue. It is an important piece of information for managers, because it tells them how much of their company’s original sales dollars remain after deducting variable cost. Contribution margin ratio is the contribution margin expressed as a percentage of sales. Contribution margin ratio can be calculate by dividing the total contribution margin by total sales or by dividing the per unit contribution margin by per unit selling prices.

Friday, November 8, 2019

Free Essays on Global Trends 2015

Global Trends 2015: Life After Pax Americana Global Trends 2015 paints a picture, which I believe to be congruent with Charles Kupchan’s article â€Å"Life After Pax Americana. Population increases are predicted to increase by over 1 billion, yet globalization – the use of technology to make the globe increasingly smaller – continues to integrate and connect the globe. After assessing the drivers and trends discussed throughout the dialogue, I feel over the course of the next decade a global landscape will emerge in which, â€Å"power and influence are more equally distributed across the globe† (Kupchan). Global demographic trends remain a factor. â€Å"The world population will increase by more than a billion by 2015, with 95 percent of that growth occurring in the developing world.† Yet in the developing-world urbanization will continue to boom, with approximatly 20-30 million of the world’s poorest people migrating to urban areas each year. These global trends will have lasting implications that will vary by state and region. Economically poorer states, or those with weak governance and infastructure, will encounter additional strains on their resources, infrastructures, and leadership. Many will attept to cope with the effects of globalization, and some will fail. At the same time, â€Å"some advanced and emerging market states – including key European and Asian allies – will be forced to reexamine longstanding political, social, and cultural precepts as they attempt to overcome the challenges of rapidly aging populations and declining workforce cohort s. In these and other cases, dem! ographic pressures will remain a potential source of stress and instability.† (Defense Intelligence Agency) In general, globalization is a positive force that will increase most of the world’s population’s standard of living, but for some, â€Å"globalization will exacerbate local and regional tensions, increase the prospects and capa... Free Essays on Global Trends 2015 Free Essays on Global Trends 2015 Global Trends 2015: Life After Pax Americana Global Trends 2015 paints a picture, which I believe to be congruent with Charles Kupchan’s article â€Å"Life After Pax Americana. Population increases are predicted to increase by over 1 billion, yet globalization – the use of technology to make the globe increasingly smaller – continues to integrate and connect the globe. After assessing the drivers and trends discussed throughout the dialogue, I feel over the course of the next decade a global landscape will emerge in which, â€Å"power and influence are more equally distributed across the globe† (Kupchan). Global demographic trends remain a factor. â€Å"The world population will increase by more than a billion by 2015, with 95 percent of that growth occurring in the developing world.† Yet in the developing-world urbanization will continue to boom, with approximatly 20-30 million of the world’s poorest people migrating to urban areas each year. These global trends will have lasting implications that will vary by state and region. Economically poorer states, or those with weak governance and infastructure, will encounter additional strains on their resources, infrastructures, and leadership. Many will attept to cope with the effects of globalization, and some will fail. At the same time, â€Å"some advanced and emerging market states – including key European and Asian allies – will be forced to reexamine longstanding political, social, and cultural precepts as they attempt to overcome the challenges of rapidly aging populations and declining workforce cohort s. In these and other cases, dem! ographic pressures will remain a potential source of stress and instability.† (Defense Intelligence Agency) In general, globalization is a positive force that will increase most of the world’s population’s standard of living, but for some, â€Å"globalization will exacerbate local and regional tensions, increase the prospects and capa...

Wednesday, November 6, 2019

Leaellynasaura - Facts and Figures

Leaellynasaura - Facts and Figures Name: Leaellynasaura (Greek for Leaellyns lizard); pronounced LAY-ah-ELL-ee-nah-SORE-ah Habitat: Plains of Australia Historical Period: Middle Cretaceous (105 million years ago) Size and Weight: About 10 feet long and 100 pounds Diet: Plants Distinguishing Characteristics: Slim build; long tail; relatively large eyes and brain About Leaellynasaura If the name Leaellynasaura sounds a bit odd, thats because this is one of the few dinosaurs to be named after a living person: in this case, the daughter of Australian paleontologists Thomas Rich and Patricia Vickers-Rich, who discovered this ornithopod in 1989. The most striking thing about Leaellynasaura is how far south it lived: during the middle Cretaceous period, the continent of Australia was relatively cold, with long, dark winters. This would explain Leaellynasauras relatively large eyes (which need to be that big in order to gather in all the available light), as well as its relatively small size, given the limited resources of its ecosystem.   Since the discovery of Leaellynasaura, many other dinosaurs have been unearthed in the southern polar regions, including the vast continent of Antarctica. (See The 10 Most Important Dinosaurs of Australia and Antarctica.) This raises an important question: while the weight of opinion is that meat-eating dinosaurs had warm-blooded metabolisms, might this also have been the case for plant-eating ornithopods like Leaellynasaura, which needed a way to protect themselves from plunging temperatures? The evidence is inconclusive, even given the recent discovery of ornithopod dinosaurs bearing feathers (which are generally evolved by warm-blooded vertebrates as a means of insulation).

Monday, November 4, 2019

Education and Organizational change Essay Example | Topics and Well Written Essays - 2500 words

Education and Organizational change - Essay Example The current demands in the labor market require a decisive approach. The changes in the labor market necessitate proportional alternations in the education systems and curriculum1. The process of measuring the educational disparities must take into consideration the socio-economic implications and the needs of the labor market. Productive employment calls for investment in human resources and the requisite competences. This calls for educational system change. This can be attributed the central role that education plays in social equity and economic productivity. Increasing the number of schooling years is perceived to be one of the strategies of ensuring that education grows to meet the changing demands of the labor markets. The education system has been blamed for being discriminatory. Children from poor background have minimal access to education. This makes the labor market a preserve of the wealthy in the society. The inequalities in the education system have had a negative impa ct on the poor in the developed and developing countries. Access to training skills and improving access to early childhood have a profound effect of the learning in the schools and job market2. This has also led to the evolution of wage gaps and stratification of the society based on the economic well being. The labor market is keen to have qualified personnel while to education system is ready to offer quality education at expensive fees. The current labor market is segmented along low and high education levels. This has also created an exclusive club of the highly paid with multiple benefits against the lowly paid with minimal benefits. Chapter 2: LITERATURE REVIEW 2.1 Labor market and human capital Addressing education is a complex affair. It must address the various levels of education and the necessary changes at each level. There is an insufficiency in terms of supply for the qualified or specialized personnel. Most of the trained young workers tend to lack the competencies t hat accompany their workplace job prescriptions. Employers blame the education systems from producing half-baked graduates. There is an urgent need to drastically change the education system of the public sector in order to improve quality. This can inject a level of equality into the education system and introduce the expected changes into the labor market. Organizations believe that productivity is closely related to the quality of employees and competencies3. The needs and the standards of the labor market have been growing and evolving over the decades. This has been attributed to the emerging wave of globalization and technological turbulence over the years. However, the education system has remained unchanged and unresponsive to the changing demands of the labor market. The tertiary education and post-secondary systems have need been customized to meet the expectation of the labor markets4. This has affected organizational performance and the national productivity in many econ omies. Universities are basing education on commercial rather that competence ideologies5. This has caused a reduction of

Friday, November 1, 2019

Animal Human Cultures Essay Example | Topics and Well Written Essays - 2000 words

Animal Human Cultures - Essay Example The proponent tries to elaborate this by pointing that humans could actually take advantage of whatever benefits they could substantially exploit from their pets. Keywords: pet keeping, animal companionship, pet, animals â€Å"The keeping of animal companions in the contemporary West is undoubtedly an exercise of domination. Despite this, different kinds of relations are possible† (Cudworth, 144). Discuss. Introduction The keeping of animal companion is a form of domination because humans are superior to any other life forms on earth with respect to different aspects. There is a significant gap, or indifference between humans and animals as agreed by Le Guin (1986). When it comes to intelligence, humans are capable of doing substantial number of great things compared to its other animal counterparts. Cudworth (2011) strongly emphasises this point by mentioning how humans could be capable of altering different breeds of pets. For instance, substantial breeds of pets are remarka ble at present. Based on the idea of Franklin (1999), the reason why this could be so it is because having companionship with pets would bring some substantial benefits for humans. In other words, genetic modifications which led to animals to become diversified in their breeds points to the fact that they are not humans in the first place. In other words, humans can take control over them and there could also be many things that they can possibly do with them. Cudworth emphasises that pets are loved because they are not humans in the first place. However, the definition of this love might be a bit problematic because this argument simply has remarkable implications in proving some important relationships existing between humans and animals. Furthermore, this argument proves that affection and love may not be synonymous after all as there must considerations of different contexts in this issue. However, it is obvious that there must be substantial form of relationships existing betwe en humans and animals in the issue of animal companionship. The proponent tries to elaborate this point clearly as possible by applying the arguments of Franklin and Cudworth in line with the issue of animal companionships. Background issue The domestication of animals provides many important things. In fact, this is the point in which humans can maximise everything out of domesticating or taking control over animals. For Cudworth this could involve having affection with them despite the very presence of domination. However, Franklin tries to include the point in which this specific affection addresses ontological insecurity. This ontological insecurity comes after the loss of paternal welfare due to market individualism in 1960s (Franklin, 1999). The keeping of animal companions boils down to the fact that humans could take care of their pets with them due to some elemental reasons. So it could be that the domestication itself is a way to orchestrate better interaction between huma ns and animals for the benefit of the former. It is true that the keeping of animals in the contemporary West is a form of domination but according to Cudworth (2011), there is affection involved in it. It is important to consider in great detail what this affection particularly means. As for the argument of Franklin, there could be essential relationship that exists in keeping animals as companions. However, his entire argument includes the major points about the benefits

Wednesday, October 30, 2019

Search Language and Search Engines Essay Example | Topics and Well Written Essays - 500 words

Search Language and Search Engines - Essay Example The numbers and letters can lead to other similar books and locations throughout the library. Search engines are also very helpful as they are a replacement of the classic style of searching. Before search engines, research could be conducted by standard index cards. The researcher would have to look through the index cards and read the catalogues to understand and be able to locate the title. Now, search engines allow the researcher to type in a few key words. These key words enable the researcher to browse through a list of titles that pertain to the researcher’s topic. One can decide to do a basic or a guided search. These two different forms of research will assist me in my search of possible sources regarding welfare reform. Using the internet to search through publications can be challenging and lead to irrelevant and false sources. The library of congress only contains credible sources and using the guided search can help narrow down specific categories of welfare reform. For example, accessing the library of congress website and choosing to perform a guided search will bring up substantial amounts of information. The guided search will bring up topics that are newer in publication and provide more current information. To the right of the search engine screen there is a date. Choosing titles with the most current date will assist in locating current